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2-Fluoromethamphetamine (2-FMA) is a rare stimulant drug of the methamphetamine family which has been used as a recreational designer drug. It is a psychoactive research chemical of the phenethylamine and substituted amphetamine chemical classes. It produces stimulant and entactogenic effects and is described subjectively as being between amphetamine and MDMA. As a recreational drug, 4-FA is sometimes sold along with related compounds such as 2-fluoroamphetamine and 4-fluoromethamphetamine.

2-FMA is popular in the Netherlands where it is predominantly used for its specific effects (77% of users) rather than its legal status (18%). 

The subjective effects of 4-fluoroamphetamine include euphoria which some find similar to the effects of MDMA and amphetamine, increased energy (stimulation), mood elevation, feelings of warmth and empathy, excessive talking, bruxism, and suppressed appetite (anorexic). The general course of effects involves primarily empathogenic effects for the first few hours, which fade out as increased stimulation develops over the next several hours.

Common acute side effects are nausea, headaches, increased heart rate, and insomnia.

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